diff --git a/packages/grid/src/vaadin-grid-keyboard-navigation-mixin.js b/packages/grid/src/vaadin-grid-keyboard-navigation-mixin.js
index 35c6d479678..b52036562dd 100644
--- a/packages/grid/src/vaadin-grid-keyboard-navigation-mixin.js
+++ b/packages/grid/src/vaadin-grid-keyboard-navigation-mixin.js
@@ -657,7 +657,41 @@ export const KeyboardNavigationMixin = (superClass) =>
         }
       }
 
-      return tabOrder[index];
+      let focusStepTarget = tabOrder[index];
+
+      // If the target focusable is tied to a column that is not visible,
+      // find the first visible column and update the target in order to
+      // prevent scrolling to the start of the row.
+      if (focusStepTarget && focusStepTarget._column && !this.__isColumnInViewport(focusStepTarget._column)) {
+        const firstVisibleColumn = this._getColumnsInOrder().find((column) => this.__isColumnInViewport(column));
+        if (firstVisibleColumn) {
+          if (focusStepTarget === this._headerFocusable) {
+            focusStepTarget = firstVisibleColumn._headerCell;
+          } else if (focusStepTarget === this._itemsFocusable) {
+            const rowIndex = focusStepTarget._column._cells.indexOf(focusStepTarget);
+            focusStepTarget = firstVisibleColumn._cells[rowIndex];
+          } else if (focusStepTarget === this._footerFocusable) {
+            focusStepTarget = firstVisibleColumn._footerCell;
+          }
+        }
+      }
+
+      return focusStepTarget;
+    }
+
+    /**
+     * Returns true if the given column is horizontally inside the viewport.
+     * @private
+     */
+    __isColumnInViewport(column) {
+      if (column.frozen || column.frozenToEnd) {
+        // Assume frozen columns to always be inside the viewport
+        return true;
+      }
+      return (
+        column._sizerCell.offsetLeft + column._sizerCell.offsetWidth >= this._scrollLeft &&
+        column._sizerCell.offsetLeft <= this._scrollLeft + this.clientWidth
+      );
     }
 
     /** @private */
diff --git a/packages/grid/src/vaadin-grid.js b/packages/grid/src/vaadin-grid.js
index 4525fad294d..7d6e3abd186 100644
--- a/packages/grid/src/vaadin-grid.js
+++ b/packages/grid/src/vaadin-grid.js
@@ -816,6 +816,10 @@ class Grid extends ElementMixin(
           cell.setAttribute('part', 'cell body-cell');
           row.appendChild(cell);
 
+          if (row === this.$.sizer) {
+            column._sizerCell = cell;
+          }
+
           if (index === cols.length - 1 && this.rowDetailsRenderer) {
             // Add details cell as last cell to body rows
             this._detailsCells = this._detailsCells || [];
diff --git a/packages/grid/test/keyboard-navigation.test.js b/packages/grid/test/keyboard-navigation.test.js
index 7583ea3e0ee..68705cb490e 100644
--- a/packages/grid/test/keyboard-navigation.test.js
+++ b/packages/grid/test/keyboard-navigation.test.js
@@ -1124,6 +1124,34 @@ describe('keyboard navigation', () => {
         left();
         expect(grid.$.table.scrollLeft).to.equal(0);
       });
+
+      it('should not scroll to the start when tabbed from header to body', () => {
+        tabToHeader();
+        end();
+        tab();
+        expect(grid.$.table.scrollLeft).to.be.at.least(100);
+      });
+
+      it('should not scroll to the start when shift-tabbed from footer to body', () => {
+        shiftTabToFooter();
+        end();
+        shiftTab();
+        expect(grid.$.table.scrollLeft).to.be.at.least(100);
+      });
+
+      it('should not scroll to the start when tabbed from body to footer', () => {
+        tabToBody();
+        end();
+        tab();
+        expect(grid.$.table.scrollLeft).to.be.at.least(100);
+      });
+
+      it('should not scroll to the start when shift-tabbed from body to header', () => {
+        tabToBody();
+        end();
+        shiftTab();
+        expect(grid.$.table.scrollLeft).to.be.at.least(100);
+      });
     });
 
     describe('vertical scrolling', () => {