diff --git a/src/cmd/cgo/internal/testsanitizers/cshared_test.go b/src/cmd/cgo/internal/testsanitizers/cshared_test.go
index 15409d0fca04fd..0cf094ead79e66 100644
--- a/src/cmd/cgo/internal/testsanitizers/cshared_test.go
+++ b/src/cmd/cgo/internal/testsanitizers/cshared_test.go
@@ -93,12 +93,19 @@ func TestShared(t *testing.T) {
 
 			cmdArgs := []string{dstBin}
 			if tc.sanitizer == "thread" && GOOS == "linux" {
-				// Disable ASLR for TSAN. See #59418.
-				arch, err := exec.Command("uname", "-m").Output()
+				// Disable ASLR for TSAN. See https://go.dev/issue/59418.
+				out, err := exec.Command("uname", "-m").Output()
 				if err != nil {
 					t.Fatalf("failed to run `uname -m`: %v", err)
 				}
-				cmdArgs = []string{"setarch", strings.TrimSpace(string(arch)), "-R", dstBin}
+				arch := strings.TrimSpace(string(out))
+				if _, err := exec.Command("setarch", arch, "-R", "true").Output(); err != nil {
+					// Some systems don't have permission to run `setarch`.
+					// See https://go.dev/issue/70463.
+					t.Logf("failed to run `setarch %s -R true`: %v", arch, err)
+				} else {
+					cmdArgs = []string{"setarch", arch, "-R", dstBin}
+				}
 			}
 			cmd = hangProneCmd(cmdArgs[0], cmdArgs[1:]...)
 			replaceEnv(cmd, "LD_LIBRARY_PATH", ".")
diff --git a/src/cmd/cgo/internal/testsanitizers/tsan_test.go b/src/cmd/cgo/internal/testsanitizers/tsan_test.go
index 9a1924968c9434..265c5e36052755 100644
--- a/src/cmd/cgo/internal/testsanitizers/tsan_test.go
+++ b/src/cmd/cgo/internal/testsanitizers/tsan_test.go
@@ -71,12 +71,19 @@ func TestTSAN(t *testing.T) {
 
 			cmdArgs := []string{outPath}
 			if goos == "linux" {
-				// Disable ASLR. See #59418.
-				arch, err := exec.Command("uname", "-m").Output()
+				// Disable ASLR for TSAN. See https://go.dev/issue/59418.
+				out, err := exec.Command("uname", "-m").Output()
 				if err != nil {
 					t.Fatalf("failed to run `uname -m`: %v", err)
 				}
-				cmdArgs = []string{"setarch", strings.TrimSpace(string(arch)), "-R", outPath}
+				arch := strings.TrimSpace(string(out))
+				if _, err := exec.Command("setarch", arch, "-R", "true").Output(); err != nil {
+					// Some systems don't have permission to run `setarch`.
+					// See https://go.dev/issue/70463.
+					t.Logf("failed to run `setarch %s -R true`: %v", arch, err)
+				} else {
+					cmdArgs = []string{"setarch", arch, "-R", outPath}
+				}
 			}
 			cmd := hangProneCmd(cmdArgs[0], cmdArgs[1:]...)
 			if tc.needsRuntime {