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Pseudocode:
-Good unit tests
-Would recommend larger sliding window
-My concern with the sliding window is that at some point you will pop off reads that had a PCR duplicate lower in the file, so that when your sliding window reaches that read, it will not recognize it as a PCR duplicate.
-I'm not sure how big your sliding window would have to be to account for this, and you're saving a lot into the window, so you can't use a window the size of a chromosome.
-Good functions to manipulate your numpy array
-Good functions for determining PCR duplication.
The text was updated successfully, but these errors were encountered:
Pseudocode:
-Good unit tests
-Would recommend larger sliding window
-My concern with the sliding window is that at some point you will pop off reads that had a PCR duplicate lower in the file, so that when your sliding window reaches that read, it will not recognize it as a PCR duplicate.
-I'm not sure how big your sliding window would have to be to account for this, and you're saving a lot into the window, so you can't use a window the size of a chromosome.
-Good functions to manipulate your numpy array
-Good functions for determining PCR duplication.
The text was updated successfully, but these errors were encountered: